product datasheet
porcn polyclonal antibody
catalog number: 27662
technical:tech@swbio.com
information:info@swbio.com
description
- swiss-prot no.:
- swiss-prot#:q9h237
ncbi gene id:64840
- form of antibody:
- avoid freeze / thaw cycles.|buffer: pbs with 50% glycerol, ph7.4.
- immunogen:
- recombinant fusion protein of human porcn (np_982299.1).
- appl_detail:
- appl_detail:
- wb 1:500 - 1:1000
- other_names:
- porcn; dhof; fodh; mg61; porc; ppn; porcupine homolog (drosophila)
- purification:
- affinity purification
- background:
- this gene belongs to the evolutionarily conserved porcupine (porc) gene family. genes of the porcupine family encode endoplasmic reticulum proteins with multiple transmembrane domains. porcupine proteins are involved in the processing of wnt (wingless and int homologue) proteins. disruption of this gene is associated with focal dermal hypoplasia, and the encoded protein has been implicated in cancer. multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
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