Product Datasheet
GIGYF2 Polyclonal Antibody
Catalog Number: 27606
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q6Y7W6
NCBI Gene ID:26058
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human GIGYF2 (NP_001096617.1).
- appl_detail:
- WB 1:500 - 1:1000
IHC 1:50 - 1:100
- other_names:
- GIGYF2; GYF2; PARK11; PERQ2; PERQ3; TNRC15; GRB10 interacting GYF protein 2
- Purification:
- Affinity purification
- Background:
- This gene contains CAG trinucleotide repeats and encodes a protein containing several stretches of polyglutamine residues. The encoded protein may be involved in the regulation of tyrosine kinase receptor signaling. This gene is located in a chromosomal region that was genetically linked to Parkinson disease type 11, and mutations in this gene were thought to be causative for this disease. However, more recent studies in different populations have been unable to replicate this association. Alternative splicing results in multiple transcript variants.
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