Product Datasheet
RNF4 Polyclonal Antibody
Catalog Number: 27598
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P78317
NCBI Gene ID:6047
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human RNF4 (NP_001171938.1).
- appl_detail:
- WB 1:500 - 1:1000
- other_names:
- RNF4; RES4-26; SLX5; SNURF; ring finger protein 4
- Purification:
- Affinity purification
- Background:
- The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.
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