Product Datasheet
DAB1 Polyclonal Antibody
Catalog Number: 27390
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:O75553
NCBI Gene ID:1600
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human DAB1 (NP_066566.3).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- DAB1; disabled homolog 1
- Purification:
- Affinity purification
- Background:
- The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain.
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