Product Datasheet
CACNA2D3 Polyclonal Antibody
Catalog Number: 27367
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q8IZS8
NCBI Gene ID:55799
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human CACNA2D3 (NP_060868.2).
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- WB 1:1000 - 1:2000
- other_names:
- CACNA2D3; HSA272268; voltage-dependent calcium channel subunit alpha-2/delta-3
- Purification:
- Affinity purification
- Background:
- This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
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