Product Datasheet
PLA2G10 Polyclonal Antibody
Catalog Number: 27347
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:O15496
NCBI Gene ID:8399
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- A synthetic peptide of human PLA2G10 (NP_003552.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- PLA2G10; GXPLA2; GXSPLA2; SPLA2; sPLA2-X; phospholipase A2 group X
- Purification:
- Affinity purification
- Background:
- This gene encodes a member of the phospholipase A2 family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This calcium-dependent enzyme hydrolyzes glycerophospholipids to produce free fatty acids and lysophospholipids. In one example, this enzyme catalyzes the release of arachidonic acid from cell membrane phospholipids, thus playing a role in the production of various inflammatory lipid mediators, such as prostaglandins. The encoded protein may promote the survival of breast cancer cells through its role in lipid metabolism.
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