Product Datasheet
SPG7 Polyclonal Antibody
Catalog Number: 27343
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9UQ90
NCBI Gene ID:6687
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human SPG7 (NP_003110.1).
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- WB 1:1000 - 1:2000
IHC 1:50 - 1:200
- other_names:
- SPG7; CAR; CMAR; PGN; SPG5C; paraplegin
- Purification:
- Affinity purification
- Background:
- This gene encodes a mitochondrial metalloprotease protein that is a member of the AAA family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Mutations in this gene cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified.
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