Product Datasheet
SEPT4 Polyclonal Antibody
Catalog Number: 27340
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:O43236
NCBI Gene ID:5414
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human 43712 (NP_536341.1).
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- WB 1:200 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
- other_names:
- SEPT4; ARTS; BRADEION; CE5B3; H5; MART; PNUTL2; SEP4; hCDCREL-2; hucep-7; septin-4
- Purification:
- Affinity purification
- Background:
- This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer.
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