Product Datasheet
SCN8A Polyclonal Antibody
Catalog Number: 27251
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9UQD0
NCBI Gene ID:6334
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human SCN8A (NP_055006.1).
- appl_detail:
- WB 1:200 - 1:1000
- other_names:
- SCN8A; BFIS5; CERIII; CIAT; EIEE13; MED; NaCh6; Nav1.6; PN4; sodium channel protein type 8 subunit alpha
- Purification:
- Affinity purification
- Background:
- This gene encodes a member of the sodium channel alpha subunit gene family. The encoded protein forms the ion pore region of the voltage-gated sodium channel. This protein is essential for the rapid membrane depolarization that occurs during the formation of the action potential in excitable neurons. Mutations in this gene are associated with mental retardation, pancerebellar atrophy and ataxia. Alternate splicing results in multiple transcript variants.
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