Product Datasheet
ATP1A Polyclonal Antibody
Catalog Number: 27234
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P05023
NCBI Gene ID:476/477/478/480
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human ATP1A (NP_000692.2).
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- WB 1:500 - 1:1000
IHC 1:50 - 1:200
IP 1:50 - 1:100
- other_names:
- ATP1A1; ATPase Na+/K+ transporting subunit alpha 1
- Purification:
- Affinity purification
- Background:
- The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene.
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