Product Datasheet
Fatty Acid Synthase Polyclonal Antibody
Catalog Number: 27231
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P49327
NCBI Gene ID:2194
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.11.
- Immunogen:
- Recombinant fusion protein of human Fatty Acid Synthase (NP_004095.4).
- appl_detail:
- WB 1:500 - 1:2000
IHC 1:50 - 1:100
IF 1:50 - 1:200
IP 1:50 - 1:100
- other_names:
- FASN; FAS; OA-519; SDR27X1; fatty acid synthase
- Purification:
- Affinity purification
- Background:
- The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
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