Product Datasheet  
SLAMF2 Antibody  
Catalog Number: 25285  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:P09326
    Gene ID:962
  • Form of Antibody:  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage:  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen:  
  • Raised against a 19 amino acid peptide near the center of human SLAMF2.
  • reactivity:  
  • Hu Ms Rt
  • appl_detail:  
  • other_names:  
  • Signaling lymphocytic activation molecule family member 2, CD48, BCM, BLAST, MEM-102
  • Purification:  
  • Affinity chromatography purified via peptide column
  • Specificity:  
  • Two isoforms of SLAMF2 are known to exist; this antibody will recognize both isoforms. SLAMF2 antibody is predicted to not cross-react with other SLAM protein family members.
  • Applications:  
  • ELISA WB
  • Background:  
  • The signaling lymphocyte-activation molecule family member 2 (SLAMF2), also known as CD48, is a GPI-anchored protein that exists as both a soluble and membrane-associated form and is expressed in almost all leukocyte populations particularly in mitogen-stimulated human lymphocytes. SLAMF2 is a high-affinity ligand for SLAMF4, also known as 2B4, as well as a low-affinity ligand for CD2, and can thus can stimulate cells expressing these receptors. It has been shown to be an IL-3-induced activating receptor on eosinophils and is likely to be involved in promoting allergic inflammation. SLAMF2 is also thought to be involved in the IL-18/IL-18R signaling cascade in T and natural killer cells to produce interferon-gamma.



 
© Signalway Biotechnology All Rights Reserved.