Product Datasheet  
PIG-Y Antibody  
Catalog Number: 24809  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q3MUY2
    Gene ID:84992
  • Form of Antibody:  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage:  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen:  
  • Raised against a 16 amino acid peptide near the center of human PIG-Y.
  • reactivity:  
  • Hu Ms
  • appl_detail:  
  • other_names:  
  • Phosphatidylinositol glycan anchor biosynthesis class Y, PreY, PIGY
  • Purification:  
  • Affinity chromatography purified via peptide column
  • Specificity:  
  • This antibody only detects isoform 1 of PIG-Y.
  • Applications:  
  • ELISA WB IHC
  • Background:  
  • Glycosylphosphatidylinositol (GPI) lipid anchoring is an important post-translational modification of proteins that takes place in the endoplasmic reticulum. The synthesis of GPI is initiated by GPI-N-acetylglucosaminyltransferase (GPI-GnT), a complex of proteins including PIG-A, PIG-H, PIG-C, GPI1, and DPM2. PIG-Y, the mammalian homolog to yeast Eri1p, is also thought to be involved in the biosynthesis of GPI. The PIG-Y gene encodes two proteins, one of which arises from leaky scanning of the mRNA.



 
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