Product Datasheet
Phospho-Src-Y419 Rabbit mAb
Catalog Number: 78148
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Storage:
- Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
- Immunogen:
- A phospho specific peptide corresponding to residues surrounding Y419 of human Phospho-Src-Y419
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- ASV, SRC1, THC6, c-SRC, p60-Src
- Purification:
- Affinity purification
- Background:
- This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
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