Product Datasheet  
AOF1 Antibody  
Catalog Number: 48421  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q8NB78
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein
  • reactivity：  
  • Hu
  • appl_detail：  
  • WB: 1:500-1:2,000
    IHC: 1:50-1:200
    ICC: 1:50-1:200

    FC: 1:100-1:200
  • other_names：  
  • amine oxidase (flavin containing) domain 1 antibody
    amine oxidase, flavin containing 1 antibody
    AOF1 antibody
    bA204B7.3 antibody
    C6orf193 antibody
    dJ298J15.2 antibody
    Flavin-containing amine oxidase domain-containing protein 1 antibody
    FLJ33898 antibody
    FLJ34109 antibody
    FLJ43328 antibody
    KDM1B antibody
    KDM1B_HUMAN antibody
    LSD2 antibody
    lysine (K)-specific demethylase 1B antibody
    Lysine-specific demethylase 2 antibody
    Lysine-specific histone demethylase 1B antibody
    Lysine-specific histone demethylase 2 antibody
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB, ICC, IHC, FC
  • Background：  
  • AOF1 (amine-oxidase flavin-containing domain 1), whose alternative names include KDM1B (lysine (K)-specific demethylase 1B) or LSD2 (lysine-specific histone demethylase 2), is an 823 amino acid nuclear protein belonging to the flavin monoamine oxidase family. As a histone demethylase, AOF1 specifically demethylates Lys4 of histone H3, a marker for epigenetic transcriptional activation, by interacting with a long stretch of the H3 N-terminal tail of mono- and dimethylated Lys4. Existing as three alternatively spliced isoforms, AOF1 is required for de novo DNA methylation of some imprinted genes in oocytes and contains a single SWIRM domain that is implicated in chromatin regulation. AOF1 contains one CW-type zinc finger and is encoded by a gene located on human chromosome 6p22.3.



 
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