Product Datasheet  
SLINGSHOT-1L Antibody  
Catalog Number: 48407  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q8WYL5
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein
  • reactivity：  
  • Hu
  • appl_detail：  

  • IHC: 1:50-1:200


    FC: 1:50-1:100
  • other_names：  
  • AW551225 antibody
    Coro1c antibody
    coronin, actin binding protein 1C antibody
    Gm1394 antibody
    Gm1395 antibody
    hSSH-1L antibody
    mSSH 1L antibody
    OTTMUSP00000031415 antibody
    Protein phosphatase Slingshot homolog 1 antibody
    Slingshot 1 antibody
    slingshot 1L antibody
    slingshot homolog 1 antibody
    slingshot like 1 antibody
    Slingshot1 antibody
    SSH 1 antibody
    SSH 1L antibody
    SSH-1L antibody
    SSH-like protein 1 antibody
    Ssh1 antibody
    SSH1_HUMAN antibody
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • IHC, FC
  • Background：  
  • Slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.



 
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