Product Datasheet  
Twist Antibody  
Catalog Number: 48345  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q15672
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • A recombinant protein corresponding to a region near the C-terminus of twist of human origin.
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  
  • WB: 1:100-1:1,000


    IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
    FC: 1 μg per 1 x 106 cells
  • other_names：  
  • ACS3 antibody
    B-HLH DNA binding protein antibody
    bHLHa38 antibody
    BPES2 antibody
    BPES3 antibody
    Class A basic helix-loop-helix protein 38 antibody
    CRS1 antibody
    H-twist antibody
    OTTHUMP00000116043 antibody
    SCS antibody
    TWIST antibody
    Twist basic helix loop helix transcription factor 1 antibody
    Twist homolog 1 (Drosophila) antibody
    Twist homolog 1 antibody
    TWIST homolog of drosophila antibody
    Twist related protein 1 antibody
    Twist-related protein 1 antibody
    TWIST1 antibody
    TWST1_HUMAN antibody
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB, IP, IF, FCM
  • Background：  
  • Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes. Class A proteins include the ubiquitously expressed E-box binding factors E12/E47, ITF2 and HEB (BETA1 or HTF4). Class B proteins such as MyoD, myogenin and NeuroD (BETA2) are transiently expressed and exhibit a much more limited tissue distribution. Class A proteins heterodimerize with class B proteins to activate DNA transcription. Working in opposition to these positively acting factors are a specialized group of proteins that function as dominant negative regulators. Muscle tissue is derived from a subset of cells originating from the embryonic mesoderm. The novel basic helix-loop-helix (bHLH) transcription factor twist is a putative regulator of mesodermal differentiation and myogenesis. Twist is expressed throughout the epithelial somite but not in the myotome. Twist requires dimerization with the E proteins and inhibits myogenic regulatory factors. It has been implicated as regulator of the temporal and spatial formation of myotomes.



 
© Signalway Biotechnology All Rights Reserved.