product datasheet
rpa2 antibody
catalog number: 42740
technical:tech@swbio.com
information:info@swbio.com
description
- swiss-prot no.:
- swiss-prot#: p15927
gene id: 6118
- form of antibody:
- rabbit igg in ph7.4 pbs, 0.05% nan3, 40% glycerol.
- immunogen:
- full length fusion protein of human rpa2
- appl_detail:
- western blotting: 1:500-1:2000
immunohistochemistry: 1:25-1:100
- other_names:
- repa2; rpa32; rp-a p32; rp-a p34
- purification:
- antigen affinity purification.
- specificity:
- the antibody detects endogenous levels of total rpa2 protein.
- background:
- replication protein a 32 kda subunit?is a?protein?that in humans is encoded by therpa2?gene. as part of the heterotrimeric replication protein a complex (rpa/rp-a), binds and stabilizes single-stranded dna intermediates, that form during dna replication or upon dna stress. it prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in dna metabolism. thereby, it plays an essential role both in dna replication and the cellular response to dna damage.
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