Product Datasheet  
Fumarase Mouse Monoclonal Antibody(2B11)  
Catalog Number: 38094  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P07954
  • Form of Antibody：  
  • Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • reactivity：  
  • Hu Rt Ms
  • appl_detail：  
  • Western blotting: 1:1000~1:3000
  • other_names：  
  • FH; Fumarase; fumarate hydratase;
  • Purification：  
  • Affinity purification using immunogen.
  • Specificity：  
  • FH Mouse Monoclonal antibody detects endogenous FH proteins.
  • Applications：  
  • WB,IF
  • Background：  
  • Fumarase (FH) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to malate. Fumarase comes in two forms: mitochondrial and cytosolic. The mitochondrial isoenzyme is involved in the Krebs Cycle (also known as the Tricarboxylic Acid Cycle [TCA] or the Citric Acid Cycle), and the cytosolic isoenzyme is involved in the metabolism of amino acids and fumarate. Subcellular localization is established by the presence of a signal sequence on the amino terminus in the mitochondrial form, while subcellular localization in the cytosolic form is established by the absence of the signal sequence found in the mitochondrial variety.



 
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