Product Datasheet  
CBR1 Monoclonal Antibody  
Catalog Number: 27187  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Uniprot: P16152

    Gene ID: 873

  • Form of Antibody：  
  • Purified mouse monoclonal in PBS(pH 7.4)containing with 0.2% sodium azide,50% glycerol.
  • Storage：  
  • store at -20˚C
  • Immunogen：  
  • Purified recombinant human CBR1 protein fragments expressed in E.coli
  • reactivity：  
  • Hu
  • appl_detail：  

  • Western blotting: 1:1000

    Immunocytochemistry: 1:100
  • other_names：  
  • 15 hydroxyprostaglandin dehydrogenase [NADP+]; 15-hydroxyprostaglandin dehydrogenase [NADP+]; Carbonyl reductase [NADPH] 1; Carbonyl Reductase 1; CBR 1; CBR1; CBR1_HUMAN; CRN; NADPH dependent carbonyl reductase 1; NADPH-dependent carbonyl reductase 1;
  • Purification：  
  • Affinity purified
  • Specificity：  
  • This antibody detects endogenous levels of CBR1,and does not cross-react with related proteins.
  • Applications：  
  • WB ICC
  • Background：  

  •  NADPH-dependent reductase with broad substrate specificity.Catalyzes the reduction of a wide variety of carbonyl compounds including quinones,prostaglandins, menadione,plus various xenobiotics.Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha.Can bind glutathione,which explains its higher affinity for glutathione-conjugated substrates.Catalyzes the reduction of S-nitrosoglutathione.




 
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