Product Datasheet  
HP1-gamma Monoclonal Antibody  
Catalog Number: 27171  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Uniprot: Q13185

    Gene ID: 11335

  • Form of Antibody：  
  • Purified mouse monoclonal antibody in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • store at -20˚C
  • Immunogen：  
  • Purified recombinant human HP1-gamma protein fragments expressed in E.coli.
  • reactivity：  
  • Ms Hu Mk Hm Rt
  • appl_detail：  

  • Western blotting: 1:1000

    Immunocytochemistry: 1:200
  • other_names：  
  • CBX 3; CBX3; CBX3_HUMAN; Chromobox homolog 3 (HP1 gamma homolog, Drosophila); Chromobox homolog 3; Chromobox protein homolog 3; GAMMA; HECH; Heterochromatin like protein 1; Heterochromatin protein 1 homolog gamma; Heterochromatin protein HP1 gamma
  • Purification：  
  • Affinity purified
  • Specificity：  
  • This antibody detects endogenous levels of HP1-gamma and does not cross-react with related proteins.
  • Applications：  
  • WB ICC IP IHC
  • Background：  

  •  Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.




 
© Signalway Biotechnology All Rights Reserved.