Product Datasheet  
Mouse anti-Human CD45, Purified mAb  
Catalog Number: 28141  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Form of Antibody：  
  • Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide
  • Storage：  
  • Store at 4°C. DO NOT FREEZE.
  • Immunogen：  
  • reactivity：  
  • Hu
  • appl_detail：  

  • Notice: This reagent has been pre-diluted for use at recommended volume per test in flow cytometry analysis. Typically add 10ul of this reagent to 100μl of experimental sample with 1 X 106 cells per test. Please refer to the detailed protocol when you perform a test.

  • other_names：  
  • Purification：  
  • Specificity：  
  • Applications：  
  • FC
  • Background：  

  •  4AA9 reacts with CD45, a 180-220 kDa leukocyte common antigen (LCA). CD45 antigen is expressed at high levels on all hematopoietic cells including T and B lymphocytes, monocytes, granulocytes, NK cells and dendritic cells, but is not expressed on non-hematopoietic cells. CD45 antibody has also been reported to react weakly with mature blood erythrocytes and platelets. CD45 is a protein tyrosine phosphatase receptor that is critically important for T and B cell antigen receptor-mediated activation.

    *Target of immunosuppresive antibody treatment.
     
    1. Knapp, W et al., eds. (1989)  Leucocyte Typing  IV: White Cell Differentiation Antigens, Oxford University Press, New York.
    2. Trowbridge, IS and Thomas, ML. (1993) Annu. Rev. Immunol. 12:85.
    3. Pulido, R et al., (1988) J. Immunol.  140:3851.
    4. Roach, T et al., (1997) Curr. Biol. 7:408.



 
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