Product Datasheet  
Mouse anti-Human CD19, Biotin Conjugated mAb  
Catalog Number: 28076  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Form of Antibody：  
  • Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
  • Storage：  
  • Store at 4°C. DO NOT FREEZE. LIGHT SENSITIVE MATERIAL.
  • Immunogen：  
  • reactivity：  
  • Hu
  • appl_detail：  

  • Vol.per.Test: 10 μl/Test

    Notice: This reagent has been pre-diluted for use at recommended volume per test in flow cytometry analysis. Typically add 10ul of this reagent to 100μl of experimental sample with 1 X 106 cells per test. Please refer to the detailed protocol when you perform a test.
  • other_names：  
  • Purification：  
  • Specificity：  
  • Applications：  
  • FC
  • Background：  

  •  COC19 reacts with CD19 (B4), a 90 kDa molecule, which is expressed on approximately 5-25% of human peripheral blood lymphocytes. CD19 antigen is present on human B lymphocytes at most stages of maturation, from the earliest Ig gene rearrangement in pro-B cells to mature cell, as well as malignant B cells, but is lost on maturation to plasma cells. CD19 antibody does not react with T lymphocytes, monocytes and granulocytes. CD19 is a critical signal transduction molecule that regulates B lymphocyte development, activation and differentiation. This clone is cross reactive with non-human primate.

    * CD19 is a key phenotyping marker of non-T cell leukemia.
     
    1.  Nadler, LM et al. (1983) J. Immunol. 131:244
    2. Schlossman, SL et al., eds. (1995)  Leucocyte Typing V: White Cell Differentiation Antigens, Oxford University Press, New York.
    3.  Tedder T. et al.  (1994)  Immunol Today. 15:437-442



 
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