Product Datasheet  
Mouse anti-Human CD14, Biotin Conjugated mAb  
Catalog Number: 28055  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Form of Antibody：  
  • Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
  • Storage：  
  • Store at 4°C. DO NOT FREEZE. LIGHT SENSITIVE MATERIAL.
  • Immunogen：  
  • reactivity：  
  • Hu
  • appl_detail：  

  • Vol.per.Test: 10 μl/Test

    Notice: This reagent has been pre-diluted for use at recommended volume per test in flow cytometry analysis. Typically add 10ul of this reagent to 100μl of experimental sample with 1 X 106 cells per test. Please refer to the detailed protocol when you perform a test.
  • other_names：  
  • Purification：  
  • Specificity：  
  • Applications：  
  • FC
  • Background：  
  •  4AW4 reacts with CD14, a 53-55 kDa molecule. CD14 is a human high affinity cell-surface receptor for complexes of lipopolysaccharide (LPS-endotoxin) and serum LPS-binding protein (LPB). CD14 antigen has a strong presence on the surface of monocytes/macrophages, is weakly expressed on granulocytes, but not expressed by myeloid progenitor cells. CD14 functions as a receptor for endotoxin; when the monocytes become activated they release cytokines such as TNF, and up-regulate cell surface molecules including adhesion molecules.This clone is cross reactive with non-human primate.
     
    1.  Knapp, W et al., eds. (1989) Leucocyte Typing IV : White Cell Differentiation Antigens, Oxford University Press, New York.
    2.  Makgoba, MW et al., (1988) Nature 331: 86-88
    3.  Boyd. AW et al. (1989) Blood  73: 1896-1903



 
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