Product Datasheet  
Mouse anti-Human CD11b, FITC Conjugated mAb  
Catalog Number: 28042  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Form of Antibody：  
  • Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA
  • Storage：  
  • Store at 4°C. DO NOT FREEZE. LIGHT SENSITIVE MATERIAL.
  • Immunogen：  
  • reactivity：  
  • Hu
  • appl_detail：  

  • Vol.per.Test: 10 μl/Test

    Notice: This reagent has been pre-diluted for use at recommended volume per test in flow cytometry analysis. Typically add 10ul of this reagent to 100μl of experimental sample with 1 X 106 cells per test. Please refer to the detailed protocol when you perform a test.
  • other_names：  
  • Purification：  
  • Specificity：  
  • Applications：  
  • FC
  • Background：  

  •  4AM216 reacts with CD11b, a member of the integrin a chain family with 165 kDa MW. which is expressed on NK cells, monocytes, granulocytes and subsets of T and B cells. It associates with CD18 to form CD11b/CD18 complex .The cellular function of CD11b is on neutrophil and monocyte interactions with stimulated endothelium; Phagocytosis of iC3b or IgG coated particles as a receptor; Chemotaxis and apoptosis.

    * CD11b is absent in Leukocyte Adhesion Deficiency (LAD-1) patients who have major problems with bacterial infections.
    This clone is cross reactive with non-human primate.
     
    1. Ling NR  et al., eds. (1987) Leucocyte Typing  III : White Cell Differentiation Antigens, Oxford University Press, New York. 303-334
    2. Petty HR nd Todd RF. (1996) Immunol. Today 17:209
    3. Springer TA (1994) Cell 76:301
    4. Stewart M et al (1995) Curr Opin Cell Biol 7:690



 
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