Product Datasheet  
PCNA Mouse Monoclonal Antibody  
Catalog Number: 21801  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P12004
    Gene ID:5111
  • Form of Antibody：  
  • Mouse IgG1 in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20°C/1 year
  • Immunogen：  
  • Mouse monoclonal antibody is prepared by immunizing a synthetic peptide.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  •  WB: 1:3000~1:10000   
     IHC: 1:200

     

  • other_names：  
  • Cyclin; DNA polymerase delta auxiliary protein; MGC8367; PCNA; Proliferating cell nuclear antigen.
  • Purification：  
  • Affinity-chromatography
  • Specificity：  
  • Applications：  
  • WB IHC
  • Background：  

  •  PCNA is a marker for cells in early G1 phase and S phase of the cell cycle. It is found in the nucleus and is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, PCNA is ubiquitinated and is involved in the RAD6 dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for PCNA. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.




 
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