Product Datasheet  
BARK1 Monoclonal Antibody  
Catalog Number: 27101  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:P13639
    Gene ID:1938
  • Form of Antibody：  
  • Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
  • Storage：  
  • Immunogen：  
  • Purified recombinant human ADRBK1(C-term.) protein fragments expressed in E.coli.
  • reactivity：  
  • Hu Rt Ms P D
  • appl_detail：  
  • Predicted MW: 80kd
    Western blotting: 1:1000
  • other_names：  
  • GRK2, BARK1, BETA-ARK1
  • Purification：  
  • Affinity purified
  • Specificity：  
  • Applications：  
  • ELISA WB
  • Background：  
  • The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1.



 
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