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TNFRSF18 Polyclonal Antibody

Catalog Number:

29368
other_names: TNFRSF18; AITR; CD357; GITR; GITR-D; TNF receptor superfamily member 18

Amount:

100μg
calculated_mw: 30kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9Y5U5
NCBI Gene ID:8784

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human TNFRSF18 (NP_683699.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

References:

appl_detail:

WB 1:500 - 1:2000

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