Lrwd1 Polyclonal Antibody

Catalog Number:

29349

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9UFC0
NCBI Gene ID:222229

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

A synthetic peptide of human Lrwd1 (NP_690852.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

WB 1:200 - 1:2000

Datasheet PDF