GYPB Polyclonal Antibody

Catalog Number:

28815

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P06028
NCBI Gene ID:2994

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human GYPB (NP_002091.3).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

IF

Background:

Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. GYPB gene consists of 5 exons and has 97% sequence homology with GYPA from the 5' UTR to the coding sequence encoding the first 45 amino acids. In addition to the M or N and S or s antigens, that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta; also, Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. Alternate splicing results in multiple transcript variants.

References:

appl_detail:

IF 1:50 - 1:200

Datasheet PDF