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EARS2 Polyclonal Antibody

Catalog Number:

28779
other_names: EARS2; COXPD12; MSE1; gluRS; glutamyl-tRNA synthetase 2, mitochondrial

Amount:

100μg
calculated_mw: 59kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q5JPH6
NCBI Gene ID:124454

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human EARS2 (NP_001295140.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes a member of the class I family of aminoacyl-tRNA synthetases. These enzymes play a critical role in protein biosynthesis by charging tRNAs with their cognate amino acids. This protein is encoded by the nuclear genome but is likely to be imported to the mitochondrion where it is thought to catalyze the ligation of glutamate to tRNA molecules. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency 12 (COXPD12). Alternative splicing results in multiple transcript variants.

References:

appl_detail:

WB 1:500 - 1:2000

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