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PMVK Polyclonal Antibody

Catalog Number:

28387
other_names: PMVK; HUMPMKI; PMK; PMKA; PMKASE; POROK1; phosphomevalonate kinase

Amount:

100μg
calculated_mw: 22kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q15126
NCBI Gene ID:10654

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human PMVK (NP_006547.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes a peroxisomal enzyme that is a member of the galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase (GHMP) family of ATP-dependent enzymes. The encoded protein catalyzes the conversion of mevalonate 5-phosphate to mevalonate 5-diphosphate, which is the fifth step in the mevalonate pathway of isoprenoid biosynthesis. Mutations in this gene are linked to certain types of porokeratosis including disseminated superficial porokeratosis. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

WB 1:500 - 1:2000

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