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CCNDBP1 Polyclonal Antibody

Catalog Number:

28328
other_names: CCNDBP1; DIP1; GCIP; HHM; cyclin-D1-binding protein 1

Amount:

100μg
calculated_mw: 42kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O95273
NCBI Gene ID:23582

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human CCNDBP1 (NP_036274.3).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene.

References:

appl_detail:

WB 1:500 - 1:2000

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