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Catalog Number: |
28306 |
other_names: | LGALS3; CBP35; GAL3; GALBP; GALIG; L31; LGALS2; MAC2; galectin-3 |
Amount: |
100μg |
calculated_mw: | 31kDa |
host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:P17931 |
Form of Antibody: |
Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4. |
Storage/Stability: |
|
Immunogen: |
Recombinant fusion protein of human LGALS3 (NP_002297.2). |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB,IF |
Background: |
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants. |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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