C3 / C3a Polyclonal Antibody

Catalog Number:

27972

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P01024
NCBI Gene ID:718

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human C3 / C3a (NP_000055.2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC,IF

Background:

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients.

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:100 - 1:200
IF 1:50 - 1:200

Datasheet PDF