1-832-868-1888
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Catalog Number: |
27818 |
other_names: | NDUFS2; CI-49; NADH:ubiquinone oxidoreductase core subunit S2 |
Amount: |
100μg |
calculated_mw: | 49kDa |
host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:O75306 |
Form of Antibody: |
Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4. |
Storage/Stability: |
|
Immunogen: |
Recombinant fusion protein of human NDUFS2 (NP_004541.1). |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB,IHC,IF |
Background: |
The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
References: |
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appl_detail: |
WB 1:1000 - 1:3000 |
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