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NDUFS2 Polyclonal Antibody

Catalog Number:

27818
other_names: NDUFS2; CI-49; NADH:ubiquinone oxidoreductase core subunit S2

Amount:

100μg
calculated_mw: 49kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O75306
NCBI Gene ID:4720

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human NDUFS2 (NP_004541.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC,IF

Background:

The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

WB 1:1000 - 1:3000
IHC 1:50 - 1:200
IF 1:50 - 1:200

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