SP3 Polyclonal Antibody

Catalog Number:

27783

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q02447
NCBI Gene ID:6670

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human SP3 (NP_003102.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

IHC

Background:

This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13.

References:

appl_detail:

IHC 1:50 - 1:200

Datasheet PDF