KRAS Polyclonal Antibody

Catalog Number:

27759

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P01116
NCBI Gene ID:3845

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human KRAS (NP_004976.2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF