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CDY2B Polyclonal Antibody

Catalog Number:

27751
other_names: CDY2B; CDY; chromodomain Y-linked 2B

Amount:

100μg
calculated_mw: 60kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9Y6F7
NCBI Gene ID:203611

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human CDY2B (NP_001001722.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This intronless gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. Two nearly identical copies of this gene are found in a palindromic region on chromosome Y; this record represents the centromeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes.

References:

appl_detail:

WB 1:1000 - 1:3000

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