PACS1 Polyclonal Antibody

Catalog Number:

27747

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q6VY07
NCBI Gene ID:55690

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human PACS1 (NP_060496.2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance.

References:

appl_detail:

WB 1:1000 - 1:3000

Datasheet PDF