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IARS Polyclonal Antibody

Catalog Number:

27322
other_names: IARS; GRIDHH; IARS1; ILERS; ILRS; IRS; PRO0785; isoleucyl-tRNA synthetase

Amount:

100μg
calculated_mw: 144kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P41252
NCBI Gene ID:3376

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human IARS (NP_002152.2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found.

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:100

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