1-832-868-1888
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Catalog Number: |
27322 |
other_names: | IARS; GRIDHH; IARS1; ILERS; ILRS; IRS; PRO0785; isoleucyl-tRNA synthetase |
Amount: |
100μg |
calculated_mw: | 144kDa |
host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:P41252 |
Form of Antibody: |
Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4. |
Storage/Stability: |
|
Immunogen: |
Recombinant fusion protein of human IARS (NP_002152.2). |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB,IHC |
Background: |
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAS, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. Alternatively spliced transcript variants have been found. |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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