SUCLA2 Polyclonal Antibody

Catalog Number:

27269

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q9P2R7
NCBI Gene ID:8803

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human SUCLA2 (NP_003841.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6.

References:

appl_detail:

WB 1:500 - 1:1000

Datasheet PDF