SLAMF4 Antibody

Catalog Number:

25287

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9BZW8
Gene ID:51744

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 16 amino acid peptide near the carboxy terminus of human SLAMF4.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

At least three isoforms of SLAMF4 are known to exist. SLAMF4 antibody is predicted to not cross-react with other SLAM protein family members.

Applications:

ELISA WB

Background:

The signaling lymphocyte-activation molecule family member 4 (SLAMF4), also known as 2B4, is an important regulator of Natural Killer (NK) cell activation. It is expressed on NK cells as well as on subsets of T cells and interacts with SLAMF2, causing the activation of both SLAMF4- and SLAMF2-expressing cells. Patients with systemic lupus erythmatosus have lower than normal levels of SLAMF4 expressed on their NK cells and monocytes, suggesting that SLAMF4 may play a role in this autoimmune disease.

References:

appl_detail:

Datasheet PDF