GNPDA2 Antibody

Catalog Number:

24849

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q8TDQ7
Gene ID:132789

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against an 8 amino acid peptide near the carboxy terminus of human GNPDA2.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

GNPDA2 antibody is predicted to not cross-react with GNPDA1.

Applications:

ELISA WB ICC

Background:

Glucosamine-6-phosphate deaminase (GNPDA) is an allosteric enzyme that catalyzes the reversible conversion of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium. GNPDA2 is the second mammalian glucosamine-6-phosphate deaminase discovered, and is closer in structure and activity to the E. coli enzyme than GNPDA1. GNPDA1 possesses greater affinity for ammonium than either GNPDA2 or the E. coli enzyme suggesting that the forward reaction of D-glucosamine-6-phosphate into D-fructose-6-phosphate and ammonium is catalyzed at a slower rate than GNPDA2.

References:

appl_detail:

Datasheet PDF