MettL7A Antibody

Catalog Number:

24790

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9H8H3
Gene ID:25840

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 13 amino acid peptide near the center of human MettL7A.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

At least two isoforms of MettL7A are known to exist. This antibody is predicted to not cross-react with MettL7B.

Applications:

ELISA WB ICC

Background:

MettL7A belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.

References:

appl_detail:

Datasheet PDF