MED4 Antibody

Catalog Number:

24727

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q9NPJ6
Gene ID:29079

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 17 amino acid peptide from near the carboxy terminus of human MED4.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

At least three isoforms of MED4 are known to exist; this antibody only recognizes the largest isoform.

Applications:

ELISA WB IHC

Background:

The mediator complex is a multi-protein transcriptional co-activator that is expressed ubiquitously in eukaryotes from yeast to mammals and is required for induction of RNA polymerase II (pol II) transcription by DNA binding transcription factor. One of the proteins in this complex is MED4. This protein has also been shown to be part of the vitamin D receptor interacting complex. MED4 was recently identified as an HIV dependency factor (HDF), suggesting that MED4 may be an important drug target in HIV treatment.

References:

appl_detail:

Datasheet PDF