1-832-868-1888
order@swbio.com
Catalog Number: |
78852 |
other_names: | IKBA;MAD-3;NFKBI;IKB alpha;NFKBIA;EDAID2 |
Amount: |
100μg |
calculated_mw: | 39kDa |
host_species: | Rabbit |
Price: |
$318 |
Swiss-Prot No: |
P25963 |
Form of Antibody: |
|
Storage/Stability: |
|
Immunogen: |
A synthesized peptide derived from human Phospho-IKB alpha (S32). |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB |
Background: |
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011] |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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