RAB7 Rabbit mAb

Catalog Number:

78560

Amount:

100μg

Price:

$318

Swiss-Prot No:

P51149

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human RAB7

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IF

Background:

RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000
IF 1:50 - 1:200

Datasheet PDF