DNA Polymerase gamma Rabbit mAb

Catalog Number:

78483

Amount:

100μg

Price:

$318

Swiss-Prot No:

P54098

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human DNA Polymerase gamma

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF