XRCC1 Rabbit mAb

Catalog Number:

78141

Amount:

100μg

Price:

$318

Swiss-Prot No:

P18887

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human XRCC1

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF